EP 30: Evidence-Based Exploration of Popular Diets with Dr. Divya D Maran

1. Howard BV, Van Horn L, Hsia J, et al. Low-fat dietary pattern and risk of cardiovascular disease: the Women’s Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006;295(6):655-666.
– Key finding: Long-term dietary intervention study of nearly 49,000 women showing modest weight loss but no significant reduction in cardiovascular disease risk

2. Mozaffarian D, Micha R, Wallace S. Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Medicine. 2010;7(3):e1000252.
– Key finding: Meta-analysis showing benefits of replacing saturated fats with polyunsaturated fats

## Low-Carb Diet Studies
3. Bueno NB, de Melo IS, de Oliveira SL, et al. Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomized controlled trials. British Journal of Nutrition. 2013;110(7):1178-1187.
– Key finding: Meta-analysis showing greater long-term weight loss with very low-carb diets compared to low-fat diets

4. Bazzano LA, Hu T, Reynolds K, et al. Effects of low-carbohydrate and low-fat diets: a randomized trial. Annals of Internal Medicine. 2014;161(5):309-318.
– Key finding: 12-month comparison showing greater weight loss and HDL improvements in low-carb group

## Paleo Diet Studies
5. Manheimer EW, van Zuuren EJ, Fedorowicz Z, Pijl H. Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis. American Journal of Clinical Nutrition. 2015;102(4):922-932.
– Key finding: Meta-analysis showing improvements in metabolic syndrome components with Paleo diet

6. Lindeberg S, Jönsson T, Granfeldt Y, et al. A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. European Journal of Clinical Nutrition. 2007;61(9):1031-1041.
– Key finding: Comparison study showing better glucose tolerance with Paleo diet versus Mediterranean diet

## Ketogenic Diet Studies
7. Levy RG, Cooper PN, Giri P. Ketogenic diet and other dietary treatments for epilepsy. Cochrane Database of Systematic Reviews. 2012;3:CD001903.
– Key finding: Review showing benefits of keto diet for epilepsy management

8. Hallberg SJ, McKenzie AL, Williams PT, et al. Effectiveness and Safety of a Novel Care Model for the Management of Type 2 Diabetes at 1 Year. Diabetes Therapy. 2018;9(2):583-612.
– Key finding: Study showing improvements in glycemic control with ketogenic diet in type 2 diabetes

## Carnivore Diet Studies
9. Tóth C, Dabóczi A, Howard M, Miller NJ, Clemens Z. Crohn’s disease successfully treated with the paleolithic ketogenic diet. Current Developments in Nutrition. 2021;5(Supplement_2):1173.
– Key finding: Case report of Crohn’s disease remission with carnivore diet

10. Bilsborough S, Crowe TC. Benefits and liabilities of plant-based diets. British Journal of Nutrition. 2003;90(3):611-620.
– Key finding: Review discussing potential risks of extreme dietary restrictions

## Mediterranean and DASH Diet Studies
11. Sofi F, Cesari F, Abbate R, Gensini GF, Casini A. Adherence to Mediterranean diet and health status: meta-analysis. BMJ. 2008;337:a1344.
– Key finding: Meta-analysis showing reduced mortality and disease risk with Mediterranean diet

12. Appel LJ, Moore TJ, Obarzanek E, et al. A clinical trial of the effects of dietary patterns on blood pressure. New England Journal of Medicine. 1997;336(16):1117-1124.
– Key finding: Original DASH trial showing significant blood pressure reduction

13. Soltani S, Arablou T, Jayedi A, Salehi‐Abargouei A. Adherence to the dietary approaches to stop hypertension (DASH) diet in relation to all‐cause and cause‐specific mortality: a systematic review and dose‐response meta‐analysis of prospective cohort studies. Advances in Nutrition. 2020;11(4):1069-1085.
– Key finding: Meta-analysis showing reduced disease risk with DASH diet adherence

## General Diet Comparison
14. Johnston BC, Kanters S, Bandayrel K, et al. Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis. JAMA. 2014;312(9):923-933.
– Key finding: Meta-analysis showing similar effectiveness among different named diet programs with adherence being key factor

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